Last Updated on August 27, 2026 by Fumipets
Temaril-P for dogs is a tablet that combines an antihistamine and a steroid, which is perfect to combat itchiness and coughing. If your dog has allergies, your veterinarian may prescribe Temaril-P (the brand name) or a generic equivalent to help provide relief from symptoms.
What Is Temaril-P for Dogs?
Temaril-P contains two medications: trimeprazine and prednisolone. Trimeprazine is an antihistamine and prednisolone is a corticosteroid. Each component tackles inflammation in a different way, providing multi-modal therapy for itchy or coughing dogs.
Temaril-P is FDA-approved for use in dogs and is available by prescription from your veterinarian. It is not a cure, but it helps control symptoms.
What Is Temaril-P Used for in Dogs?
Since it contains an antihistamine and a steroid, Temaril-P is great to relieve itch, curb inflammation, and reduce coughing. Common uses in dogs include:
Veterinarians often prescribe Temaril-P to help get a flare-up of allergies or bronchitis under control, but it can also be used long term to manage allergy symptoms. Your dog will start off at the full dose for his weight for about four days, then your veterinarian will give instructions to gradually taper the dose. Your goal is to find the lowest dose that is effective to keep your dog feeling his best.
Side Effects of Temaril P for Dogs
Both components of Temaril-P can cause side effects, including ones you will recognize as prednisone side effects in dogs.
Potential side effects include:
- Increased thirst and drinking
- Increased urination
- Increased appetite
- Drowsiness
- Vomiting
- Diarrhea
- Immunosuppression and being more susceptible to infections
- Low body temperature
- Low blood pressure
- Tremors
- Weakness
- Weight loss
Increased drinking, urination, and appetite are all quite common when giving steroids. These effects will go away as you taper the dose and discontinue the medication. Give Temaril-P with food to minimize GI side effects.
Thankfully, the combination of trimeprazine with prednisolone means that the two drugs work together, providing relief for your dog at lower doses than if he was getting one drug by itself. This lowers the risk of side effects.
If your dog needs to take Temaril-P long term, you may see signs of Cushing’s disease such as a thinning coat, fragile skin, muscle loss, potbellied appearance, delayed wound healing, and abnormal heart rate. If you notice any of these symptoms in your dog, contact your veterinarian.
An overdose of Temaril-P can be dangerous. Signs that your dog has consumed too much Temaril-P include lethargy, seizures, incoordination, and extremely low blood pressure. If your dog gets into a bottle of Temaril-P, contact your veterinarian or Pet Poison Hotline immediately.
